<p><b>A.</b> Venn diagram to show the intersection between genes down-regulated in LPS stimulated EOC 13.31 cells by miR-146a over-expression, and those up-regulated upon miR-146a knock-down. Also shown are those targets bioinformatically predicted using the TargetScan 5.1 program and IPA software. <b>B.</b> Schematic showing alterations in expression in key inflammatory response-related genes in LPS stimulated EOC 13.31 cells following miR-146a over-expression. Colored green are those down-regulated genes, colored red are up-regulated genes, while those highlighted in blue are bioinformatically predicted targets of miR-146a using the TargetScan 5.1 program and IPA software.</p
<p>Schematic representation of molecules in the EGFR/Akt signaling pathway that are inhibited by miR...
<p>RAW264.7 cells were exposed to 1 or 3 h of hypoxia and followed by various periods (2, 4, or 6 h)...
<p>A) This gene network was built with IPA software and down-regulated potential targets are highlig...
<p><b>A.</b> Venn diagram to show the intersection between genes down-regulated by miR-146a over-exp...
<p>Genes listed in bold are those that are bioinformatically predicted to be targets of miR-146a usi...
<p>Down-regulated genes are in bold italics, up-regulated genes are in plain type.</p
MicroRNAs (miRNAs) are non-coding RNA sequences involved in post-transcriptional gene regulation of ...
<p>Quantitative real-time PCR of miR-146a. (<b>A</b>) miR-146a expression after transfection with LN...
<p>Anti-miR-146a suppresses the miR-146a levels and rescues target gene expression levels. (<b>A</b>...
<p>A summary showing key inflammatory response-related genes whose expression is modulated upon the ...
Excessive or inappropriate activation of the immune system can be deleterious to the organism, warra...
The microRNA, miR-146a, is a negative feedback regulator of the central immune transcription factor,...
(A) FPKM values of Targetscan-predicted miR-146a-5p target Traf6 in WT or miR-146a-/- ATMs during HF...
<p>(<b>A–C</b>) Quantitative real-time PCR of IRAK-1 (A), IRAK-2 (B) and TRAF-6 (C) expression 24 ho...
<p>NSCLC cell lines were transfected with miR-146a inhibitor, miR-146a mimic, EGFR-specific siRNA an...
<p>Schematic representation of molecules in the EGFR/Akt signaling pathway that are inhibited by miR...
<p>RAW264.7 cells were exposed to 1 or 3 h of hypoxia and followed by various periods (2, 4, or 6 h)...
<p>A) This gene network was built with IPA software and down-regulated potential targets are highlig...
<p><b>A.</b> Venn diagram to show the intersection between genes down-regulated by miR-146a over-exp...
<p>Genes listed in bold are those that are bioinformatically predicted to be targets of miR-146a usi...
<p>Down-regulated genes are in bold italics, up-regulated genes are in plain type.</p
MicroRNAs (miRNAs) are non-coding RNA sequences involved in post-transcriptional gene regulation of ...
<p>Quantitative real-time PCR of miR-146a. (<b>A</b>) miR-146a expression after transfection with LN...
<p>Anti-miR-146a suppresses the miR-146a levels and rescues target gene expression levels. (<b>A</b>...
<p>A summary showing key inflammatory response-related genes whose expression is modulated upon the ...
Excessive or inappropriate activation of the immune system can be deleterious to the organism, warra...
The microRNA, miR-146a, is a negative feedback regulator of the central immune transcription factor,...
(A) FPKM values of Targetscan-predicted miR-146a-5p target Traf6 in WT or miR-146a-/- ATMs during HF...
<p>(<b>A–C</b>) Quantitative real-time PCR of IRAK-1 (A), IRAK-2 (B) and TRAF-6 (C) expression 24 ho...
<p>NSCLC cell lines were transfected with miR-146a inhibitor, miR-146a mimic, EGFR-specific siRNA an...
<p>Schematic representation of molecules in the EGFR/Akt signaling pathway that are inhibited by miR...
<p>RAW264.7 cells were exposed to 1 or 3 h of hypoxia and followed by various periods (2, 4, or 6 h)...
<p>A) This gene network was built with IPA software and down-regulated potential targets are highlig...