NADPH oxidase deficient-mice control parasitemia, but succumb to infection with <i>T. cruzi</i>.

<p>WT, <i>phox</i> KO and <i>inf-γ</i> KO mice were infected with 1000 blood-born trypomastigotes of Y strain of <i>T. cruzi</i>. Parasitemia (A) and mortality (B) were accessed daily. (A) Points represent mean ± SE of 5 animals per group of one from three different experiments performed with similar results. Asterisks represent P<0.05 by Student's <i>t</i> test. (B) Mortality curve is pooled from three different experiments and P<0.05 among all groups in the graph.