<i>phox</i> KO mice control parasite proliferation in target organs.

<p>WT, <i>phox</i> KO and <i>inf-γ</i> KO mice infected with <i>T. cruzi</i> were sacrificed on days 10 and 15 post-infection and tissue parasitism in spleen, heart and liver evaluated by real-time PCR as described in material and methods. Bars represent mean ± SE of four animals per group. Arrows indicate P<0.05 between WT and <i>phox</i> KO animals. The parasitism of <i>ifn-γ</i> KO group is statistically different from WT and <i>phox</i> groups in all organs and times analyzed, except for the heart at day 10 post-infection.