<i>NEUROG2</i>-transduced SVZ cells extend dendrites into the molecular layer and innervate the target CA3 in vivo.

<p>Similar to endogenous DG granule neurons, the <i>NEUROG2</i>-transduced SVZ cells extended elaborate dendrites into the molecular layer (A-A′), which were positive for Map2 (B-B′″). The <i>NEUROG2</i>-transduced SVZ cells also expressed the axonal initial segment marker Ankyrin G (C-C′″) and displayed DsRed+ processes in the CA3 (Regions 1–3) (D-D′″). Some of these processes were positive for the neuronal marker βIIItubulin (E-E′″), suggesting the ability of the <i>NEUROG2</i>-transduced SVZ neurons to innervate the CA3. Scale bar = 20 µm.