<p>There is a significant decrease in the numbers of CD3, CD8 and CD4 positive cells in acute uncomplicated <i>P. falciparum</i> malaria (D0, circles), compared to cell numbers during convalescence in the same donors (D28, triangles). The number of CD4 positive cells on convalescence remains significantly lower than age- and sex- matched healthy controls (squares). The number of CD19 positive B-cells doesn't significantly differ. <b><sup>a</sup></b><i>P</i> value calculated using Wilcoxon rank statistical comparison of matched pairs. <b><sup>b</sup></b><i>P</i> value calculated using the Mann-Whitney U comparison of unpaired data.</p
textabstractBoth γδ T cells and CD4+ T cells have been implicated in immunity to malaria, but their ...
<p>A) Blood samples from acute malaria patients and healthy controls were analyzed <i>ex-vivo</i> fo...
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in m...
<p>A. Flow cytometry plots demonstrating increased expression of PD-1 on CD4<sup>+</sup> T-cells (to...
<p>T<sub>reg</sub> frequencies of CD4+ T cells (FoxP3+CD25+CD127<sup>dim</sup>) were measured at 16,...
<p>A. The overall malaria-specific CD4<sup>+</sup> T cell response (left column) is followed by the ...
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in m...
Vδ2+ γδ T cells are semi-innate T cells that expand markedly following P. falciparum (Pf) infection ...
Naturally acquired immunity to malaria may be lost with lack of exposure. Recent heterogeneous reduc...
BACKGROUND: The immune mechanisms that determine whether a Plasmodium falciparum infection would be ...
<p>Regulatory T cell frequencies were analyzed as the percentage of FoxP3+CD25+ of CD4+ T cells from...
BACKGROUND: Plasmodium falciparum malaria remains a major cause of illness and death in sub-Saharan ...
a<p>A total of 53 SP (26 aged 4–8 years, 27 aged 9–14 years) and 29 SN (14 aged 4–8 years, 15 aged 9...
<p>Shown are the percentages of B memory cell responders to <i>P. falciparum</i> antigens, AMA1 and ...
<p>(<b>A</b>) PBMCs were collected from 34 healthy children with blood smears negative for <i>P. fal...
textabstractBoth γδ T cells and CD4+ T cells have been implicated in immunity to malaria, but their ...
<p>A) Blood samples from acute malaria patients and healthy controls were analyzed <i>ex-vivo</i> fo...
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in m...
<p>A. Flow cytometry plots demonstrating increased expression of PD-1 on CD4<sup>+</sup> T-cells (to...
<p>T<sub>reg</sub> frequencies of CD4+ T cells (FoxP3+CD25+CD127<sup>dim</sup>) were measured at 16,...
<p>A. The overall malaria-specific CD4<sup>+</sup> T cell response (left column) is followed by the ...
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in m...
Vδ2+ γδ T cells are semi-innate T cells that expand markedly following P. falciparum (Pf) infection ...
Naturally acquired immunity to malaria may be lost with lack of exposure. Recent heterogeneous reduc...
BACKGROUND: The immune mechanisms that determine whether a Plasmodium falciparum infection would be ...
<p>Regulatory T cell frequencies were analyzed as the percentage of FoxP3+CD25+ of CD4+ T cells from...
BACKGROUND: Plasmodium falciparum malaria remains a major cause of illness and death in sub-Saharan ...
a<p>A total of 53 SP (26 aged 4–8 years, 27 aged 9–14 years) and 29 SN (14 aged 4–8 years, 15 aged 9...
<p>Shown are the percentages of B memory cell responders to <i>P. falciparum</i> antigens, AMA1 and ...
<p>(<b>A</b>) PBMCs were collected from 34 healthy children with blood smears negative for <i>P. fal...
textabstractBoth γδ T cells and CD4+ T cells have been implicated in immunity to malaria, but their ...
<p>A) Blood samples from acute malaria patients and healthy controls were analyzed <i>ex-vivo</i> fo...
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in m...