Re-introduction of divalent cations following EDTA evokes Ca²⁺ influx in vagal neurons.

<p>Mean ± S.E.M. Ca²⁺ responses of vagal neurons in response to brief treatment with EDTA (5 mM; 0 Ca²⁺, 0 Mg²⁺) followed by re-introduction of Ca²⁺ (2.2 mM) and Mg²⁺ (1.2 mM) as measured by Fura 2AM. Response to capsaicin (1 µM) and KCl (75 mM) also shown. Data comprised of capsaicin-sensitive (black squares; n = 41) and capsaicin-insensitive neurons (grey squares; n = 11) from C57BL/6 mice. Blocked line denotes application of drugs.