Adiponectin in CR serum promotes insulin receptor and eNOS phosphorylation, resulting in NO^• release.

<p>(<b>A</b>) Adiponectin levels in AL and CR sera before and after immunoprecipitation (IP). (<b>B</b>) Tyr phosphorylation in insulin receptors immunoprecipitated from homogenates of VSMC cultured for 24 h in the presence of CR or AL serum, with (IP) or without (Control) prior adiponectin immunoprecipitation. (<b>C</b>) eNOS^Ser1177 phosphorylation in homogenates from VSMC cultured for 24 h in the presence of CR or AL serum, with (IP) or without (Control) prior adiponectin immunoprecipitation. (<b>D</b>) NO₂⁻ levels in the media from VSMC cultured for 24 h in the presence of CR or AL serum, with (IP) or without (Control) prior adiponectin immunoprecipitation. *p<0.05 versus AL; ^#p<0.05 versus control. Representative blots, shown above quantifications, were cut to remove other bands, without any further image manipulation.