<p>Mice were challenged with influenza 1 day after a single inhaled treatment with the described treatments. Shown are survival (<b>A</b>) and body weight (<b>B</b>) of mice through 22 days after challenge (mean ± s.d.). (n = 20 mice/group; * p<0.00001 vs. PBS treated, ** p = 0.0004 vs. PBS treated, † p = 0.01 vs. Pam2+ODN 2006 treated, † p = 0.1 vs Pam2+ODN 2006 treated).</p
Secondary bacterial pneumonia is a frequent complication of influenza, associated with high morbidit...
Abstract Background Viral respiratory infections may promote bacterial super-infection decreasing th...
<p>(A-D) Wild-type C57BL/6J mice were either treated with the CD73 inhibitor (α,β- methylene ADP), t...
<p>Swiss-Webster mice were challenged with influenza A/Hong Kong/8/68 (H3N2) 24 h after aerosolized ...
<p>Mice were challenged with influenza 1 day after a single inhaled treatment with Pam2 and ODN. Sho...
<p>Mice were challenged with influenza 1 day after a single inhaled treatment with the described tre...
<p>Mice were challenged with influenza A following a single aerosolized treatment with Pam2-ODN 3 d ...
(A) Survival of wildtype mice treated with Pam2-ODN or PBS (sham) by aerosol 24 h before challenge w...
<p>C57Bl/6 mice were injected intravenously with 25 ug of 5′pppRNA in complex with in vivo-jetPEI. (...
<p>BALB/c mice (n = 18) were immunized i.m. twice, 8 weeks apart, with 0.1 μg of SAM(NP), SAM(M1), S...
<p>Mice were treated with 5′pppRNA in complex in vivo-jetPEI on the day prior to influenza infection...
We have previously discovered a synergistically therapeutic combination of two Toll-like receptor (T...
<p>Animals were immunized and challenged as described in <a href="http://www.plosone.org/article/inf...
<p>C57/BL6 mice were challenged with H1N1 (10<sup>5</sup> pfu/mouse, i.t.) for up to 6 days. For com...
<p>(A-B) 24 h after i.p. infection with ~2.1–3.2x10<sup>4</sup> CFU of exponential phase PJ-1324 (~2...
Secondary bacterial pneumonia is a frequent complication of influenza, associated with high morbidit...
Abstract Background Viral respiratory infections may promote bacterial super-infection decreasing th...
<p>(A-D) Wild-type C57BL/6J mice were either treated with the CD73 inhibitor (α,β- methylene ADP), t...
<p>Swiss-Webster mice were challenged with influenza A/Hong Kong/8/68 (H3N2) 24 h after aerosolized ...
<p>Mice were challenged with influenza 1 day after a single inhaled treatment with Pam2 and ODN. Sho...
<p>Mice were challenged with influenza 1 day after a single inhaled treatment with the described tre...
<p>Mice were challenged with influenza A following a single aerosolized treatment with Pam2-ODN 3 d ...
(A) Survival of wildtype mice treated with Pam2-ODN or PBS (sham) by aerosol 24 h before challenge w...
<p>C57Bl/6 mice were injected intravenously with 25 ug of 5′pppRNA in complex with in vivo-jetPEI. (...
<p>BALB/c mice (n = 18) were immunized i.m. twice, 8 weeks apart, with 0.1 μg of SAM(NP), SAM(M1), S...
<p>Mice were treated with 5′pppRNA in complex in vivo-jetPEI on the day prior to influenza infection...
We have previously discovered a synergistically therapeutic combination of two Toll-like receptor (T...
<p>Animals were immunized and challenged as described in <a href="http://www.plosone.org/article/inf...
<p>C57/BL6 mice were challenged with H1N1 (10<sup>5</sup> pfu/mouse, i.t.) for up to 6 days. For com...
<p>(A-B) 24 h after i.p. infection with ~2.1–3.2x10<sup>4</sup> CFU of exponential phase PJ-1324 (~2...
Secondary bacterial pneumonia is a frequent complication of influenza, associated with high morbidit...
Abstract Background Viral respiratory infections may promote bacterial super-infection decreasing th...
<p>(A-D) Wild-type C57BL/6J mice were either treated with the CD73 inhibitor (α,β- methylene ADP), t...