Comparison of T cell subpopulations between pigs that died during acute infection versus survivors.

<p>The differences in CD4+ and CD8+ cell subpopulations during the acute infection with NiV up to 7 dpi. Values, based on flow cytometry analysis, were arbitrarily set as 50% at 0 dpi. The solid line represents piglets that died at 7 dpi, the dashed line represents the survivors. Standard Error is represented as error bars for 2 pigs per each group/mean value. Survivors had significantly higher values for the CD4−CD8+ (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030855#pone-0030855-g008" target="_blank"><b>Fig. 8.A</b></a>) at 7 dpi compare to the piglets which died at that day. Marked difference was observed for the CD4+CD8− T lymphocytes (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030855#pone-0030855-g008" target="_blank"><b>Fig. 8.B</b></a>). The down-trend starting almost immediately post infection for this cell subpopulation in pigs that died due to NiV infection was especially pronounced. In contrast, there was an up-regulation of CD4+CD8− T helper cells at 2 dpi in the survivors.