Nitrite+erythrocytes inhibited ATP release from platelets induced by ADP (A), collagen (B), and U46619 (C).

<p>PRP+erythrocytes (20% hematocrit) were incubated with 0.1 µM nitrite in the presence and absence of 200 µM C-PTIO for 5 min. The ATP release was induced by 20 µM ADP, 2.5 µg/mL collagen or 1 µM U46619. ^*<i>P</i><0.05 compared with PRP+erythrocytes and PRP+erythrocytes+nitrite+C-PTIO (ANOVA). All experiments were performed at 37°C. Data are means ± SEM (n = 5).