Effect of mepyramine and JNJ 7777120 on BAL-fluid cellularity.

<p>Mice were sensitized to, and provoked with, OVA and treated with DMSO, mepyramine, JNJ 7777120, or mepyramine plus JNJ 7777120 either 30 min before each provocation cycle (<i>A</i>) or 30 min before and 2 h after each injection for sensitization (<i>B</i>). As control, mice were sensitized with PBS (sham), provoked with OVA, and treated with DMSO. Cells in BAL-fluids, collected 24 h after the final challenge, were differentially counted. Data shown are means ± SD (n_(sham) = 3, n_(DMSO) = 7, n_{(mepyramine, JNJ 7777120, or mepyramine+JNJ 7777120)} = 8; *, p≤0.05; **, p≤0.01; ***, p≤0.005).