MPTP induced astrogilal activation is suppressed in ASK1<sup>−/−</sup> mice.
- Kang-Woo Lee (335658)
- Xin Zhao (71840)
- Joo-Young Im (335660)
- Hilary Grosso (335661)
- Won Hee Jang (335662)
- Teresa W. Chan (335663)
- Patricia K. Sonsalla (335664)
- Dwight C. German (335665)
- Hidenori Ichijo (185177)
- Eunsung Junn (335666)
- M. Maral Mouradian (335668)
Publication date
February 2013
DOIAbstract
<p>(A, B) Immunohistochemistry for GFAP in nigral (SNc) and striatal (ST) sections. Scale bar = 100 µm. (C) Quantification of nigral GFAP immunopositivity. * p<0.01; **<0.001. (D) Quantification of striatal GFAP immunopositivity. ** p<0.001. Quantifications were done using ImageJ. WT-Saline (n = 4), WT-MPTP-1 day (n = 4), WT-MPTP-3 day (n = 4); ASK1<sup>−/−</sup>-Saline (n = 3), ASK1<sup>−/−</sup>-MPTP-1 day (n = 4), ASK1<sup>−/−</sup>-MPTP-3 day (n = 3).</p
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