IL-8 release induced by CCHFV is higher than that induced by DUGV.

<p>(A) IL-8 released into the maintenance medium was assayed by ELISA and represented as IL-8 fold increase ratio comparing to mock-infected cells; (B) Expression levels of the IL-8 gene were quantified by by real time qRT-PCR, using mean ± sd of three independent experiments performed in duplicate. ―♦― mock-infected cells; --•--, infection at MOI of 1; ―▴―, infection at MOI of 0.1 (CCHFV in black and DUGV in grey); --▪--, UV-inactivated CCHFV.