Histological injury 24 hours after renal ischemia-reperfusion injury in wild type and AMPK-β1^−/− mice.

<p>IRI was performed for 20 minutes and the severity of injury was assessed by histology. A. Histological appearance at 24 hours following 20 mins IRI in WT and β1^−/− mice. Images shown are from the region of the corticomedullary junction (CMJ). 200× magnification. The severity of histological injury at 24-hours was quantified in cortex (B), CMJ (C) and medulla (D) as described in methods. No differences were seen between WT and β1^−/− mice. n = 7 for WT and 6 for β1^−/−.