Compositional nucleotide biases in the first and last letters of the minimal absent words in selected sets of minimal absent words in four human genome assemblies.

<p>Green slices represent the fraction of A nucleotides, blue slices represent the fraction of C nucleotides, yellow slices represent the fraction of G nucleotides, and red slices represent the fraction of T nucleotides. GRCh37 is the reference human genome assembly build 37.1, HuRef is the genome of Craig Venter, NA12878 is the human genome assembly from cell line GM12878, and YH is the genome of a Han Chinese individual. For each human genome assembly, set contains all minimal absent words (MAWs) of length 11 bp, set contains all MAWs of length 50 bp, set contains all MAWs of length 100 bp, set contains all MAWs of length 300 bp, and set contains all MAWs of length 1,000 bp. The noRC area displays results without considering the reversed complement and the withRC area displays results considering the reversed complement.