Model parameters.

<p>Parameter sensitivity analysis. Model parameters and their values. Sensitivity was determined by varying individual parameters by +/−5% and +/−50% while holding the other parameters at their defined values. The sensitivity of a parameter was classified as High if either a +/−5% change in its value caused a change in the fit of the data of over 25%. Similarly, the sensitivity of a parameter was Medium if either a +/−50% change in value caused a change in the fit of the data of over 25%, and Low if the +/−50% change in value did not change the fit by more than 25%. Two data sets were used to conduct this analysis: 90 min 5HT and 5×5 min 5HT with 15 min washes. List ordered by sensitivity to 5×5 min 5HT. Parameters indicted with a * were replaced with the following in an alternate model: k_A2 = 2, k_DAGp = 2, k_DAGd = 200, k_A1 = 200,000, k_A3 = 2, and k_A4 = 0.08.