<p>A. Macroscopic pictures of representative rat AAAs 14 days after elastase perfusion. B. External diameter increase at 14 days as a percentage of AAA diameters just after elastase perfusion. C. Macroscopic pictures of mouse AAAs at 14 day. D. Mouse external and internal aortic diameter quantification. Open circles represent individual values from vehicle- and CsA-treated animals and closed circles represent means±SD. *P<.05, **P<0.01 <i>vs</i> vehicle.</p
<p>A, Representative images of elastica van Gieson-stained tissue of EP4<sup>+/−</sup>/ApoE<sup>−/−<...
An abdominal aortic aneurysm (AAA) is a potentially fatal cardiovascular disease with multifactorial...
Transverse aortic constriction (TAC) is a frequently used model to investigate pressure overload-ind...
<p>A. Experimental design: rats with already formed, expanding AAAs were treated for 7 days with veh...
<p>A. Representative anti-αSMA immunostaining performed on AAA cross sections from vehicle- or CsA-t...
<p><b>(A)</b> Representative aortas are shown at zero, one, and six weeks (w) after application of C...
<p>(a) Representative aortic images are shown at zero (0 w), one (1 w), and six weeks (6 w) after th...
<p>A, Representative images of elastica van Gieson-stained tissue of EP4<sup>+/−</sup> and EP4<sup>+...
<p>A. Effect of the administration of a blocking antibody against active TGF-beta on the stabilizing...
<p>AAAs diameter was measured by using ultrasonography. An AAA was defined as a more than 50% increa...
<p>(A) Gross morphology of abdominal aorta with indicated interventions. The arrow indicates a typic...
<p>(<b>A-B</b>) Immediately after CaCl<sub>2</sub> treatment, Gelfoam patches loaded with PBS (CaCl<...
<p>(A) Consistent Temporal Pattern of AAA Development. Temporal evolution of AAA demonstrating the e...
<p>(<b>A</b>) Representative <i>ex vivo</i> pictures of aortas harvested from ApoE<sup>-/-</sup> mic...
<p><b>A</b>. Ultrasonic measurements of abdominal aortic diameters of calpain-1 +/+ and −/− mice adm...
<p>A, Representative images of elastica van Gieson-stained tissue of EP4<sup>+/−</sup>/ApoE<sup>−/−<...
An abdominal aortic aneurysm (AAA) is a potentially fatal cardiovascular disease with multifactorial...
Transverse aortic constriction (TAC) is a frequently used model to investigate pressure overload-ind...
<p>A. Experimental design: rats with already formed, expanding AAAs were treated for 7 days with veh...
<p>A. Representative anti-αSMA immunostaining performed on AAA cross sections from vehicle- or CsA-t...
<p><b>(A)</b> Representative aortas are shown at zero, one, and six weeks (w) after application of C...
<p>(a) Representative aortic images are shown at zero (0 w), one (1 w), and six weeks (6 w) after th...
<p>A, Representative images of elastica van Gieson-stained tissue of EP4<sup>+/−</sup> and EP4<sup>+...
<p>A. Effect of the administration of a blocking antibody against active TGF-beta on the stabilizing...
<p>AAAs diameter was measured by using ultrasonography. An AAA was defined as a more than 50% increa...
<p>(A) Gross morphology of abdominal aorta with indicated interventions. The arrow indicates a typic...
<p>(<b>A-B</b>) Immediately after CaCl<sub>2</sub> treatment, Gelfoam patches loaded with PBS (CaCl<...
<p>(A) Consistent Temporal Pattern of AAA Development. Temporal evolution of AAA demonstrating the e...
<p>(<b>A</b>) Representative <i>ex vivo</i> pictures of aortas harvested from ApoE<sup>-/-</sup> mic...
<p><b>A</b>. Ultrasonic measurements of abdominal aortic diameters of calpain-1 +/+ and −/− mice adm...
<p>A, Representative images of elastica van Gieson-stained tissue of EP4<sup>+/−</sup>/ApoE<sup>−/−<...
An abdominal aortic aneurysm (AAA) is a potentially fatal cardiovascular disease with multifactorial...
Transverse aortic constriction (TAC) is a frequently used model to investigate pressure overload-ind...