Effects of METH injections and SCH23390 treatment on the expression of stress response regulated proteins.

<p>(A) Representative immunoblots showing the effects of METH and SCH23390. (A–E) Pretreatment with SCH23390 blocked the METH-induced changes on ATF3 (B), ATF4 (C), CHOP (D) and caspase-12 (E). Protein expression was normalized to α-Tubulin. Key to statistics: * = p<0.05; *** = p<0.001, in comparison to the Saline group. ## = p<0.01; ### = p<0.001, in comparison to the SCH group. !! = p<0.01; !!! = p<0.001, in comparison of METH group to the SCH+METH group.