Association of <i>C3</i> haplotype blocks with wet AMD.

<p>OR: odds ratio; CI: confidence intervals.</p><p>The association of haplotype CC in block 4 remained statistically significant after correction for multiple testing (permutation <i>P</i> = 0.011).</p><p>*The <i>P</i>-values were calculated by the chi-square test on haplotype counts (1 degree of freedom).</p>†<p>The omnibus <i>P</i>-values were calculated by the PLINK software (4 degrees of freedom for block 1; 2 degrees of freedom for block 2, 4, and 5; 3 degrees of freedom for block 3).