Effect of function blocking anti-gal-1 antibodies and lactose on adhesion of HTR-8/SVneo cells to plastic, collagen type I, fibronectin and Matrigel.

<p>Adhesion was studied after 1 h (A, C) or 2 h (B, D) using anti-gal-1 antibody (1 µg/ml in A and B; 5 µg/ml in C and D) in adhesion to uncoated or precoated wells. The relevance of lectin-type interactions for extravillous trophoblast cell adhesion was assessed in the presence of 0.1 M lactose after 1 h and 2 h (E, F). Data (from three experiments in triplicate) are expressed as percentages of non-immune IgG or untreated controls, with values given as mean ± S.E.M., and statistical significance as * for <i>P</i><0.05, ** for <i>P</i><0.01 and *** for <i>P</i><0.001.