<p>The odds ratios for MS are shown according to the number of risk alleles carried. The reference value is based on the a priori probability of someone in the general population to carry MS risk alleles. A) Weighted risk scores for the 6 genotyped SNPs including <i>HLA-DRB</i>. B) Weighted risk scores for the 5 genotyped SNPs.</p
Multiple sclerosis (MS) develops as a result of environmental influences on the genetically suscepti...
<p>The Genetic Risk Score (GRS) was calculated as the number of risk alleles in rs7206790, rs1164494...
<p>The tertiles of the weighted genotype scores comprised five risk SNPs (rs17119975, rs4417316, rs6...
<p><i>The wGRS was calculated by multiplying the number of risk alleles by the weight of each SNP an...
<p>In brief, GWAS statistics (OR and risk allele frequencies) are used to simulate a population of 1...
<p>Distribution of the seven SNPs-based genetic risk score in 1,387 NPC cases (black bars) and 1,459...
<p>The risk alleles considered are the variant alleles of rs7574865, rs3099844 and rs3024505 SNPs.</...
In genomewide association study (GWAS) of a complex phenotype, a large number of variants, many with...
<p>Weighted Genetic Risk Scores from GWAS SNPs and their associations with BMI in Sample B.</p
<p>wGRS (weighted Genetic Risk Score) has been calculated using the ORs for the 52 non-HLA MS suscep...
<p><i>Categories of risk were defined based on the 95%CI of risk of each individual (see methods). G...
<p> indicates the number of SNP markers used in the model being evaluated. All other values indicate...
<p>Allelic components of the presented haplotypes are rs3787138, rs1044396 and rs3787140 SNPs, respe...
<p>The box indicates the interquartile range, bisected by the median, and the whiskers the range. Fu...
<p>The risk associated with carriage of the HLA-DRB1*1501 haplotype is given; for the risks associat...
Multiple sclerosis (MS) develops as a result of environmental influences on the genetically suscepti...
<p>The Genetic Risk Score (GRS) was calculated as the number of risk alleles in rs7206790, rs1164494...
<p>The tertiles of the weighted genotype scores comprised five risk SNPs (rs17119975, rs4417316, rs6...
<p><i>The wGRS was calculated by multiplying the number of risk alleles by the weight of each SNP an...
<p>In brief, GWAS statistics (OR and risk allele frequencies) are used to simulate a population of 1...
<p>Distribution of the seven SNPs-based genetic risk score in 1,387 NPC cases (black bars) and 1,459...
<p>The risk alleles considered are the variant alleles of rs7574865, rs3099844 and rs3024505 SNPs.</...
In genomewide association study (GWAS) of a complex phenotype, a large number of variants, many with...
<p>Weighted Genetic Risk Scores from GWAS SNPs and their associations with BMI in Sample B.</p
<p>wGRS (weighted Genetic Risk Score) has been calculated using the ORs for the 52 non-HLA MS suscep...
<p><i>Categories of risk were defined based on the 95%CI of risk of each individual (see methods). G...
<p> indicates the number of SNP markers used in the model being evaluated. All other values indicate...
<p>Allelic components of the presented haplotypes are rs3787138, rs1044396 and rs3787140 SNPs, respe...
<p>The box indicates the interquartile range, bisected by the median, and the whiskers the range. Fu...
<p>The risk associated with carriage of the HLA-DRB1*1501 haplotype is given; for the risks associat...
Multiple sclerosis (MS) develops as a result of environmental influences on the genetically suscepti...
<p>The Genetic Risk Score (GRS) was calculated as the number of risk alleles in rs7206790, rs1164494...
<p>The tertiles of the weighted genotype scores comprised five risk SNPs (rs17119975, rs4417316, rs6...