<p>Glomeruli were isolated from both WT and Tg26 mice treated with vehicle or BD4 for 6 weeks. Total RNA was isolated from the glomeruli for real-time PCR analysis for the podocyte differentiation markers including synaptopodin, nephrin, and WT-1 (<b>A</b>) as well as for RARα and RARβ (<b>B</b>). The ratio of these genes normalized to GAPDH was calculated. n = 6, *p<0.01 compared to vehicle-treated WT mice (WT-vehicle), **p<0.05 compared to vehicle-treated Tg26 mice (Tg26-vehicle), ***p<0.05 compared to vehicle-treated WT mice (WT-vehicle).</p
<p>(A and B) The glomerular lysates from the control and <i>Tjp1<sup>△pod</sup></i> mice at 1 week a...
<p>Slit diaphragm proteins nephrin (a–b) and podocin (c–d) are observed as linear line around capill...
<p>(A) Immunofluorescence study of the Tie2 receptor in mouse glomerulus. The staining of Tie2 (gree...
<p><b>A.</b> Mouse podocytes cultured at 37°C for 10 days and then stimulated with either ATRA, or A...
<p>(A) The expression of the podocyte markers WT1, synaptopodin and nephrin was immunohistochemicall...
The podocyte is a remarkable cell type, which encases the capillaries of the kidney glomerulus. Alth...
<p>(<b>a</b> and <b>b</b>) Expression of mRNAs encoding podocyte proteins and GN-associated genes in...
Glomerular podocytes are highly specialized epithelial cells and play an essential role in establish...
<p>(<b>a</b>) Glomerular localization of podocin, NMIIA, synaptopodin, vimentin, and WT1 in C57BL/6 ...
<p>Quantitative RT-PCR analysis of the expression of genes involved in the podocyte structure such a...
<p>(A) WT1 expression in MRL/lpr mice (starting at 12 weeks of age, 6 per group), as shown by immuno...
<p>(A) Western blotting detected expression of CD31 and synaptopodin in NS-treated and ADR-treated k...
BACKGROUND: The podocyte is a remarkable cell type, which encases the capillaries of the kidney glom...
<p>Representative WT-1 positive cell (podocyte marker), PECAM-1 (endothelial cell marker), TUNEL-pos...
A) R26Sun1-2xsf-GFP-6xmyc/+ female mice were bred with Wt1eGFPCre/+ males. Upon Cre-mediated recombi...
<p>(A and B) The glomerular lysates from the control and <i>Tjp1<sup>△pod</sup></i> mice at 1 week a...
<p>Slit diaphragm proteins nephrin (a–b) and podocin (c–d) are observed as linear line around capill...
<p>(A) Immunofluorescence study of the Tie2 receptor in mouse glomerulus. The staining of Tie2 (gree...
<p><b>A.</b> Mouse podocytes cultured at 37°C for 10 days and then stimulated with either ATRA, or A...
<p>(A) The expression of the podocyte markers WT1, synaptopodin and nephrin was immunohistochemicall...
The podocyte is a remarkable cell type, which encases the capillaries of the kidney glomerulus. Alth...
<p>(<b>a</b> and <b>b</b>) Expression of mRNAs encoding podocyte proteins and GN-associated genes in...
Glomerular podocytes are highly specialized epithelial cells and play an essential role in establish...
<p>(<b>a</b>) Glomerular localization of podocin, NMIIA, synaptopodin, vimentin, and WT1 in C57BL/6 ...
<p>Quantitative RT-PCR analysis of the expression of genes involved in the podocyte structure such a...
<p>(A) WT1 expression in MRL/lpr mice (starting at 12 weeks of age, 6 per group), as shown by immuno...
<p>(A) Western blotting detected expression of CD31 and synaptopodin in NS-treated and ADR-treated k...
BACKGROUND: The podocyte is a remarkable cell type, which encases the capillaries of the kidney glom...
<p>Representative WT-1 positive cell (podocyte marker), PECAM-1 (endothelial cell marker), TUNEL-pos...
A) R26Sun1-2xsf-GFP-6xmyc/+ female mice were bred with Wt1eGFPCre/+ males. Upon Cre-mediated recombi...
<p>(A and B) The glomerular lysates from the control and <i>Tjp1<sup>△pod</sup></i> mice at 1 week a...
<p>Slit diaphragm proteins nephrin (a–b) and podocin (c–d) are observed as linear line around capill...
<p>(A) Immunofluorescence study of the Tie2 receptor in mouse glomerulus. The staining of Tie2 (gree...