Vaginal washes from mice treated with cellulose sulfate 6% gel inhibit HSV-2 plaque formation.

<p>To remove any residual drug within the vaginal lumen prior to HSV-2 challenge in the safety studies, vaginal washes were obtained with 100 µl of saline. The vaginal washes were tested in a viral plaque assay. Results are means (SEM) from 2 independent experiments with pooled washes from 5 mice each; the asterisk denotes p<0.05.