The phenotype of bone marrow derived DC is not affected by absence of CTSD.

<p>Bone marrow cells from CTSD −/− and CTSD +/+ donor chimeras were cultured in GM-CSF for seven days, purified on CD11c magnetic beads, and then analysed for expression of surface markers by flow cytometry. Cells were >80% CD11c positive. Shaded histogram: isotype control. Solid line : CTSD −/− DC. Dotted line CTSD +/+ DC. One of three experiments.