<p>Total number of embryos recovered at each stage is indicated; number of dead embryos is included in parenthesis.</p>a<p>Mutant homozygous (<i>Ikbkap<sup>3loxP/3loxP</sup></i> or <i>Ikbkap<sup>Δ20/Δ20</sup></i>) or compound heterozygous (<i>Ikbkap<sup>3loxP/Δ20</sup></i>) embryos were recovered at Mendelian ratio at E9.5 and E10.5.</p>b<p>The majority of the embryos recovered were alive and appeared to be one day delayed.</p>c<p>∼75% of the embryos were alive, appeared to be one day delayed and exhibited impaired cephalic development and severe cardiac abnormalities, see results.</p
<p><b>A.</b> A1: fluorescence in situ hybridization detected <i>Pik3c3</i> mRNA expression (red) in ...
<p>Embryos were transfected/electroporated with IKBKAP shRNAs (A,B) or control shRNAs (C,D) at St. 1...
© 2020 Wolters Kluwer Medknow Publications. All rights reserved. Objective: To investigate morphokin...
<p>(<b>A</b>) Wild-type embryo at E8.5. Mutant Ikbkap<sup>3loxP/3loxP</sup> (<b>B</b>) and Ikbkap<su...
<p>(<b>A–F</b>) H&E-stained transverse sections through the head of E9.5 WT (<b>A</b> and <b>D</b>),...
<p><b>A.</b> Representative images of cultured blastocysts from a heterozygous control embryo. Embry...
<p>(A) Compared to controls (A-i and A-v), homozygous female E10.5 X<i><sup>UtxGT1</sup></i> X<i><su...
<p>Embryonic Day 9.5 and 10.5 mp66α −/− Embryos. Mutant embryos, significantly smaller, are shown in...
<p>(A) Survival rate of IKK<sup>MyHC</sup> embryos with expression of IKK2-CA transgene (i.e. in the...
<p><sup>a</sup> Total number obtained, with the number inviable, i.e. dead or severely abnormal, in ...
To investigate the prevalence, developmental potential, chromosomal constitution and clinical outcom...
<p>At 8.5 dpc mutant embryos are indistinguishable from their wild-type littermates. From 9.5 dpc on...
© 2020 Wolters Kluwer Medknow Publications. All rights reserved. Objective: To investigate morphokin...
© 2020 Wolters Kluwer Medknow Publications. All rights reserved. Objective: To investigate morphokin...
<p>In <i>gyc76C</i><sup><i>2388</i></sup> heterozygous embryos (A) the DT lumen is continuous (A, ar...
<p><b>A.</b> A1: fluorescence in situ hybridization detected <i>Pik3c3</i> mRNA expression (red) in ...
<p>Embryos were transfected/electroporated with IKBKAP shRNAs (A,B) or control shRNAs (C,D) at St. 1...
© 2020 Wolters Kluwer Medknow Publications. All rights reserved. Objective: To investigate morphokin...
<p>(<b>A</b>) Wild-type embryo at E8.5. Mutant Ikbkap<sup>3loxP/3loxP</sup> (<b>B</b>) and Ikbkap<su...
<p>(<b>A–F</b>) H&E-stained transverse sections through the head of E9.5 WT (<b>A</b> and <b>D</b>),...
<p><b>A.</b> Representative images of cultured blastocysts from a heterozygous control embryo. Embry...
<p>(A) Compared to controls (A-i and A-v), homozygous female E10.5 X<i><sup>UtxGT1</sup></i> X<i><su...
<p>Embryonic Day 9.5 and 10.5 mp66α −/− Embryos. Mutant embryos, significantly smaller, are shown in...
<p>(A) Survival rate of IKK<sup>MyHC</sup> embryos with expression of IKK2-CA transgene (i.e. in the...
<p><sup>a</sup> Total number obtained, with the number inviable, i.e. dead or severely abnormal, in ...
To investigate the prevalence, developmental potential, chromosomal constitution and clinical outcom...
<p>At 8.5 dpc mutant embryos are indistinguishable from their wild-type littermates. From 9.5 dpc on...
© 2020 Wolters Kluwer Medknow Publications. All rights reserved. Objective: To investigate morphokin...
© 2020 Wolters Kluwer Medknow Publications. All rights reserved. Objective: To investigate morphokin...
<p>In <i>gyc76C</i><sup><i>2388</i></sup> heterozygous embryos (A) the DT lumen is continuous (A, ar...
<p><b>A.</b> A1: fluorescence in situ hybridization detected <i>Pik3c3</i> mRNA expression (red) in ...
<p>Embryos were transfected/electroporated with IKBKAP shRNAs (A,B) or control shRNAs (C,D) at St. 1...
© 2020 Wolters Kluwer Medknow Publications. All rights reserved. Objective: To investigate morphokin...