Tc17 and Th17 cells, and the Th17∶Tc17 ratio in ITP patients and controls.

<p>(a) Significantly elevated percentage of Tc17 was found in newly-diagnosed ITP patients (median, 0.79%; range, 0.25–3.58%) compared to controls (median, 0.30%; range, 0.04–1.80%; ***<i>P</i><0.0001) and CR patients (median, 0.39%; range, 0.10–1.54%; **<i>P</i> = 0.0017). (b) Statistically elevated percentage of Th17 cells was found in newly-diagnosed ITP patients (median, 2.24%; range, 0.72–8.18%) compared to controls (median, 1.19%; range, 0.04–4.53%; **<i>P</i> = 0.0016; [similar to our previous study]). (c) The Th17∶Tc17 ratio in newly-diagnosed patients (median, 2.5850; range, 1.4221–3.0714) was 0.76-fold lower than controls (median, 3.3852; range, 1.0000–5.8571; ***<i>P</i><0.0001) and 0.70-fold lower than CR cases (median, 3.6771; range, 2.3896–5.5000; ***<i>P</i><0.0001).