MCP-1-deficiency has no impact on astrocyte activation.

<p>Whole hemisphere GFAP-stained images comparing the activation of astrocytes between wildtype and MCP-1-deficient animals. Analyses showed no differences with respect to immunoreactivity and morphology between wildtype and MCP-1-deficient mice. GFAP staining showed the common distribution and activation of astrocytes reacting to oxygen deprivation. Astrogliosis occurred primarily surrounding the infarcted core in both wildtype and MCP-1-deficient mice.