Gal 3/LPS interaction decreases mice resistance to the lethality of LPS.

<p><b>A</b>: Groups of 5 Balb/C mice were challenged with PBS, 6.2, 12.5 or 25 mg/kg of <i>E. coli</i> LPS by intraperitoneal (ip) injection. <b>B</b>: Mice (5 per group) were challenged with 500 µl of PBS, Gal 3 (40 µM), 6.2 mg/kg LPS or with a mixture of LPS (6.2 mg/kg) and Gal 3 (40 µM) preincubated for 15 min. The mortality rate was monitored regularly and represented as percentage of survival. *p<0.05.