<p>(A) Decreased tumor incidence and mean tumor volume after NRP-2 knockdown. Tumor incidence (10 mice) after liver injection with CNDT 2.5 shcntr cells or one of two shNRP-2 clones. (B) Top: Final liver tumor volumes in mice injected with shcntr and shNRP-2 clones. Bottom: Representative images of tumors. (C) Immunoblot analysis of NRP-2 in tumors from mice injected with CNDT 2.5 shcntr or shNRP-2 C6 cells [‘T1’; Tumor #1; ‘T2’; Tumor #2]. β-Actin served as a loading control.</p
<p>A. Overall view of tumors formed by NIH3T3-flagOVA66. Tumors in nude mice were seen after injecti...
<p>Male nude mice injected with the human prostate tumor line DU145 (4×10<sup>6</sup>), were treated...
<p>A: The number and size of most of tumor in rats injected with phps1 (a specific inhibitor of Shp2...
<p>(<i>A</i>) Autoradiographic image of the array membrane showing differential expression of metast...
<p>(A) Immunohistochemical staining for NRP-2 expression in representative tissue sections (20X) of ...
<p>(A) Real-time PCR quantification of <i>SRC-2</i>, <i>SHP</i>, <i>CADM4</i>, and <i>DKK4</i> expre...
<p>(A) Tumor volumes after administration of sicntr and siNRP-2 liposomes. Nude mice (7 per group) w...
<p>After transfection of control shRNA or <i>RBPJ</i> shRNA, 1×10<sup>6</sup> RD cells were subcutan...
<p>A. Tumor growth curve of after injection of nude mice with SATB2 or vector control (plncx2) expre...
<p>(<b>A</b>) Representative photographs of splenic primary tumors (<i>arrow</i>s) and liver metasta...
<p>PANC-1 SP and NSP cells were orthotopically inoculated s.c. to the left dorsal flank of mice. On ...
<p><i>A, B</i>: The macroscopic observation of nude mice bearing subcutaneous NOS2 (A) and NOS2TR (B...
<p>(A) Annexin V assay on shcntr and shNRP-2 CNDT 2.5 cells after treatment without or with 5FU for ...
<p>B6 mice were given control Ig or PK136 on day −3 and day 0 (i.p.) followed by i.v. injection of B...
<p>(A) Validation of two independent shRNAs for their ability to lower RXR-α protein levels in hepat...
<p>A. Overall view of tumors formed by NIH3T3-flagOVA66. Tumors in nude mice were seen after injecti...
<p>Male nude mice injected with the human prostate tumor line DU145 (4×10<sup>6</sup>), were treated...
<p>A: The number and size of most of tumor in rats injected with phps1 (a specific inhibitor of Shp2...
<p>(<i>A</i>) Autoradiographic image of the array membrane showing differential expression of metast...
<p>(A) Immunohistochemical staining for NRP-2 expression in representative tissue sections (20X) of ...
<p>(A) Real-time PCR quantification of <i>SRC-2</i>, <i>SHP</i>, <i>CADM4</i>, and <i>DKK4</i> expre...
<p>(A) Tumor volumes after administration of sicntr and siNRP-2 liposomes. Nude mice (7 per group) w...
<p>After transfection of control shRNA or <i>RBPJ</i> shRNA, 1×10<sup>6</sup> RD cells were subcutan...
<p>A. Tumor growth curve of after injection of nude mice with SATB2 or vector control (plncx2) expre...
<p>(<b>A</b>) Representative photographs of splenic primary tumors (<i>arrow</i>s) and liver metasta...
<p>PANC-1 SP and NSP cells were orthotopically inoculated s.c. to the left dorsal flank of mice. On ...
<p><i>A, B</i>: The macroscopic observation of nude mice bearing subcutaneous NOS2 (A) and NOS2TR (B...
<p>(A) Annexin V assay on shcntr and shNRP-2 CNDT 2.5 cells after treatment without or with 5FU for ...
<p>B6 mice were given control Ig or PK136 on day −3 and day 0 (i.p.) followed by i.v. injection of B...
<p>(A) Validation of two independent shRNAs for their ability to lower RXR-α protein levels in hepat...
<p>A. Overall view of tumors formed by NIH3T3-flagOVA66. Tumors in nude mice were seen after injecti...
<p>Male nude mice injected with the human prostate tumor line DU145 (4×10<sup>6</sup>), were treated...
<p>A: The number and size of most of tumor in rats injected with phps1 (a specific inhibitor of Shp2...