Effects of chronic corticosterone treatment on TrkB mRNA levels in the frontal cortex and hippocampus.

<p>CD-1 male mice were treated with corticosterone (CORT; 35 ug/ml/day) or vehicle (0.45% hydroxypropyl-β-cyclodextrin) for 7 weeks. TrkB mRNA levels were determined by qRT-PCR analysis. The level of TrkB mRNA was normalized to that of RPS3 RNA in the same sample. Values are expressed as fold change relative to vehicle-treated mice. Open and filled bars represent vehicle and corticosterone-treated groups, respectively. Error bars represent standard Error (SE) of n = 4 mice per group.