Epithelial NOS2 mRNA expression and NO release are induced by T cells but not HRV14.

<p>HNEC were either not infected (C) or exposed apically to HRV14 alone (HRV), or co-cultured with activated T cells alone (T cells), or exposed to HRV14 washed thoroughly then co-cultured with activated T cells (HRV+T cells). (A) mRNA was determined by real-time PCR and data represented as fold increase relative to non-infected cells cultured without T cells. (B) NO secretion is expressed as the amount of nitrite (the stable oxidation product of NO) released in the apical and basolateral compartments (µM). Shown are the boxplots with the 25^th, 50^th (median), 75^th percentiles, the mean (open square), the maximum and the minimum values. *p<0.05. **p<0.05 compared with HRV-infected cells.