Mmp10 expression correlates with cancer stem cell genotypes and metastasis in human lung tumors.

<p><b>A</b>) Gene expression data from primary human lung adenocarcinomas were divided into two groups of 30 samples consisting of lowest (Low) and highest (High) Mmp10 expressing lung tumors. n = 30; * p = 2.8×10⁻³³. <b>B</b>) Mmp10 in normal lung versus lung tumors with (<b><i>Met.</i></b>) and without (<b><i>No Met.</i></b>) bone metastases. n = 3, normals, n = 9, No Mets, n = 7, Met.; NS = not significant, *p = 0.008; **p = 0.04. <b>C</b>) Mmp10 mRNA expression in human tumors. Data are expressed as fold-change from matched normal.