Cholesterol depletion with MβCD increases VGCC currents and maximal conductance.
- Erin K. Purcell (341932)
- Liqian Liu (107431)
- Paul V. Thomas (107434)
- R. Keith Duncan (107444)
Publication date
February 2013
DOIAbstract
<p>Representative traces (A) and I-V curves (B) demonstrate increased calcium currents following MβCD treatment (p<0.001, ANOVA) without an effect on membrane capacitance. Boltzmann fits to G–V curves (C) demonstrate increased maximal conductance (Gmax) and a rightward shift in Vhalf following MβCD treatment (D). * = p<0.05, *** = p<0.001.</p
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