Influences of pallidal reserpine infusion on locomotor activity and social interaction.

<p>EGF and control (CON) rats received local reserpine- or vehicle-infusion to both hemispheres of the GP. (A) Cannula placement was confirmed in fixed brains, and two out of 36 rats were excluded from the final data analysis due to incorrect cannula placement. (B) Two hours after pallidal infusion, rats were placed in the automated activity monitoring chamber for 60 min. Data represent horizontal movement (cm) for every 5 min (mean ± SEM, N = 7–9 for each group). (C) Following locomotor test, an unfamiliar male rat was placed in the same chamber. The number and duration of sniffing behaviors of operated rats were counted for 10 min. Bars indicate mean ± SEM (N = 8–9 for each group). **p<0.01, ***p<0.001 by Fisher's LSD, compared with vehicle-infused controls.