<p>Apo E-knockout mice were fed a Western-type diet and treated with PBS (control group) (n = 10) or 1 mg/kg/day 15d-PGJ<sub>2</sub> (15d-PGJ<sub>2</sub> group) (n = 10) for 2 mo. Representative cross-sections of the aortic sinus were stained with MOMA-2 (A), which detected macrophages, and MCP-1 Abs (B), MIF Abs (C), TNF-α Abs (D), MMP-9 Abs (E), PPARγ Abs (F), and counterstained with hematoxylin. Right sections are control group and left ones are 15d-PGJ<sub>2</sub> group in each figure. Black arrows indicate the positive lesions.</p
<p>(A) Representative sections in <i>Ldlr</i><sup>−/−</sup> mice fed a regular chow diet (0 M) or HF...
<p>The cross-sections were from the aortic root in each group, and these were chosen from mice whose...
<p>(A) Photomicrograph of lesions observed in atherosclerotic aortas as analyzed with elastin/van Gi...
<p>Representative photomicrographs and quantification of maximum plaque area (panels A-C). Represent...
<p>Representative photomicrographs and quantification of maximum plaque area (panels A–C). Represent...
<p><b>A</b>. Lesions from Pg infected <i>Ldlr</i>° mice had greater cellularity and reduced collagen...
<p><b>A</b>. Representative Mac-2 staining of suprarenal aortas form Ang II-treated and Ang II+clopi...
<p>(A) Representative photograph of Oil-Red-O and macrophage (MOMA-2) staining of atherosclerotic pl...
<p>Apo E-/- mice (n = 10/group) were transplanted with splenocytes (left upper panel) or bone marrow...
<p>Aortic sinus sections were studied in LDLR<sup>−/−</sup>p110γ<sup>+/−</sup> (females, <i>n</i> = ...
Ldlr-/- mice were fed Western diet and treated with 5 or 15 mg/kg MPO inhibitor PF-06282999 PO, BID ...
<p>(A,B) Representative images of oil red O-stained atherosclerotic lesions in aortic sinus. (C,D) I...
<p>Real-time PCR analysis shows (A) Cytokines- IL1β, TGFβ, TNFα and IFNγ- decreased, but (B) MCP1, M...
<p>A. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections w...
<p>(A) Saline treated mouse tissue (B) demonstrates reduced macrophage invasion with Serp-1 treatmen...
<p>(A) Representative sections in <i>Ldlr</i><sup>−/−</sup> mice fed a regular chow diet (0 M) or HF...
<p>The cross-sections were from the aortic root in each group, and these were chosen from mice whose...
<p>(A) Photomicrograph of lesions observed in atherosclerotic aortas as analyzed with elastin/van Gi...
<p>Representative photomicrographs and quantification of maximum plaque area (panels A-C). Represent...
<p>Representative photomicrographs and quantification of maximum plaque area (panels A–C). Represent...
<p><b>A</b>. Lesions from Pg infected <i>Ldlr</i>° mice had greater cellularity and reduced collagen...
<p><b>A</b>. Representative Mac-2 staining of suprarenal aortas form Ang II-treated and Ang II+clopi...
<p>(A) Representative photograph of Oil-Red-O and macrophage (MOMA-2) staining of atherosclerotic pl...
<p>Apo E-/- mice (n = 10/group) were transplanted with splenocytes (left upper panel) or bone marrow...
<p>Aortic sinus sections were studied in LDLR<sup>−/−</sup>p110γ<sup>+/−</sup> (females, <i>n</i> = ...
Ldlr-/- mice were fed Western diet and treated with 5 or 15 mg/kg MPO inhibitor PF-06282999 PO, BID ...
<p>(A,B) Representative images of oil red O-stained atherosclerotic lesions in aortic sinus. (C,D) I...
<p>Real-time PCR analysis shows (A) Cytokines- IL1β, TGFβ, TNFα and IFNγ- decreased, but (B) MCP1, M...
<p>A. Representative photomicrographs showing immunofluorescence staining of aortic sinus sections w...
<p>(A) Saline treated mouse tissue (B) demonstrates reduced macrophage invasion with Serp-1 treatmen...
<p>(A) Representative sections in <i>Ldlr</i><sup>−/−</sup> mice fed a regular chow diet (0 M) or HF...
<p>The cross-sections were from the aortic root in each group, and these were chosen from mice whose...
<p>(A) Photomicrograph of lesions observed in atherosclerotic aortas as analyzed with elastin/van Gi...