<p>Each subject provided a sample 1 day after injection and two more over the course of 28 days. The serum penicillin G half life is 4.1 days. At approximately day 11 the expected mean penicillin G serum level is less than 0.02 µg/ml. On days 1, 2 and 3 the 95% confidence intervals extend upward beyond 0.13 and are truncated to allow more visual resolution at the lower end of the curve. (Note: day 21 outlier removed from calculation of mean; see text.).</p
<p>A) Cell viability measured by OD<sub>600</sub> vs time (Key:+: no antibiotic, blue diamond: 1 <b>...
In the clinical study researchers want to answer the most important question whether a new therapy i...
<p>Standard patient (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.01773...
<p>Logarithmic trend-line estimates are shown for each protection level. As days progress, the perce...
<p>Mean serum penicillin G levels and 95% confidence intervals for days since injection.</p
When introduced in the 1950s, benzathine penicillin G (BPG) was shown to be effective in eradicating...
<p>Time point 1-2-3-4 are 20, 40, 60 and 80 minutes after bolus injection. The green bar is the mean...
<p>Assays contained variable concentrations of penicillin G (0.05–1000 µM) with fixed concentrations...
<p>Open symbols: Calculated sample curves for 2 hr (green) and 24 hr (purple) injections using the s...
<p>Mean (standard deviation) BG00010 serum concentrations over (a) 120 h and (b) 15 h (expanded time...
Within a few years after the first successful clinical use of penicillin, investigations were conduc...
<p>Control 1, saline; Control 2, PEN 12,500; Contro 3, PEN 15,000; Experimental 1, PA; Experimental ...
<p>Mean and 95% confidence interval for hemoglobin measured at baseline and routine study follow-up ...
Survival ratio of RGCs in each experimental group (% relative to the normal untreated group) at 30 d...
Introduction: Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary ...
<p>A) Cell viability measured by OD<sub>600</sub> vs time (Key:+: no antibiotic, blue diamond: 1 <b>...
In the clinical study researchers want to answer the most important question whether a new therapy i...
<p>Standard patient (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.01773...
<p>Logarithmic trend-line estimates are shown for each protection level. As days progress, the perce...
<p>Mean serum penicillin G levels and 95% confidence intervals for days since injection.</p
When introduced in the 1950s, benzathine penicillin G (BPG) was shown to be effective in eradicating...
<p>Time point 1-2-3-4 are 20, 40, 60 and 80 minutes after bolus injection. The green bar is the mean...
<p>Assays contained variable concentrations of penicillin G (0.05–1000 µM) with fixed concentrations...
<p>Open symbols: Calculated sample curves for 2 hr (green) and 24 hr (purple) injections using the s...
<p>Mean (standard deviation) BG00010 serum concentrations over (a) 120 h and (b) 15 h (expanded time...
Within a few years after the first successful clinical use of penicillin, investigations were conduc...
<p>Control 1, saline; Control 2, PEN 12,500; Contro 3, PEN 15,000; Experimental 1, PA; Experimental ...
<p>Mean and 95% confidence interval for hemoglobin measured at baseline and routine study follow-up ...
Survival ratio of RGCs in each experimental group (% relative to the normal untreated group) at 30 d...
Introduction: Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary ...
<p>A) Cell viability measured by OD<sub>600</sub> vs time (Key:+: no antibiotic, blue diamond: 1 <b>...
In the clinical study researchers want to answer the most important question whether a new therapy i...
<p>Standard patient (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.01773...