<p>Immunohistochemical analysis human GRP transplant-derived cells does not reveal expression of the astrocyte glutamate transporter, GLT1, in the SOD1<sup>G93A</sup> spinal cord at disease endstage (<b>A</b>–<b>C</b>). Intraspinal levels of GLT1 were measured using Western blotting of whole cervical spinal cord segments at C5. hGRPs did not slow the loss of intraspinal GLT1 protein levels compared to hF controls (<b>D</b>). Asterisks denote regions with large numbers of transplant-derived cells, but no GLT1 expression. Scale bars: 200 µm.</p
A major portion of spinal cord injury (SCI) cases affect midcervical levels, the location of the phr...
The GLT-1 and GLAST astroglial transporters are the glutamate transporters mainly involved in mainta...
<p><b>(A, B)</b>- Qualitative analysis of GAD65 and synaptophysin immuoreactivity showed normally ap...
<p>Transplanted HuNA<sup>+</sup> hGRPs differentiated into GFAP<sup>+</sup> astrocytes by disease en...
<p>HuNA<sup>+</sup> hGRP transplant-derived cells did not differentiate into βIII-Tubulin<sup>+</sup...
<p>Unlike the lack of hGRP survival observed in SOD1<sup>G93A</sup> mice with CSA-based immune suppr...
<p>Human GRP transplant-derived cells (from 4 injection sites: bilaterally at C4 and C5) dispersed t...
<p>All SOD1<sup>G93A</sup> animals had significantly reduced phrenic CMAP amplitudes at 120 days of ...
<p>Approximately 10% of transplant-derived HuNA<sup>+</sup> cells continued to divide at disease end...
<p>Greater cell survival was found with the “high dose” transplants compared to “low dose” transplan...
Cellular abnormalities are not limited to motor neurons in amyotrophic lateral sclerosis (ALS). Ther...
<p>At disease endstage, HuNA<sup>+</sup> cells co-labeled with the oligodendrocyte lineage marker, O...
A major portion of spinal cord injury (SCI) cases affect midcervical levels, the location of the phr...
<p>Immunohistochemical analysis revealed a decrease in GLT1 protein expression two (B) and six weeks...
Transplantation-based replacement of lost and/or dysfunctional astrocytes is a promising therapy for...
A major portion of spinal cord injury (SCI) cases affect midcervical levels, the location of the phr...
The GLT-1 and GLAST astroglial transporters are the glutamate transporters mainly involved in mainta...
<p><b>(A, B)</b>- Qualitative analysis of GAD65 and synaptophysin immuoreactivity showed normally ap...
<p>Transplanted HuNA<sup>+</sup> hGRPs differentiated into GFAP<sup>+</sup> astrocytes by disease en...
<p>HuNA<sup>+</sup> hGRP transplant-derived cells did not differentiate into βIII-Tubulin<sup>+</sup...
<p>Unlike the lack of hGRP survival observed in SOD1<sup>G93A</sup> mice with CSA-based immune suppr...
<p>Human GRP transplant-derived cells (from 4 injection sites: bilaterally at C4 and C5) dispersed t...
<p>All SOD1<sup>G93A</sup> animals had significantly reduced phrenic CMAP amplitudes at 120 days of ...
<p>Approximately 10% of transplant-derived HuNA<sup>+</sup> cells continued to divide at disease end...
<p>Greater cell survival was found with the “high dose” transplants compared to “low dose” transplan...
Cellular abnormalities are not limited to motor neurons in amyotrophic lateral sclerosis (ALS). Ther...
<p>At disease endstage, HuNA<sup>+</sup> cells co-labeled with the oligodendrocyte lineage marker, O...
A major portion of spinal cord injury (SCI) cases affect midcervical levels, the location of the phr...
<p>Immunohistochemical analysis revealed a decrease in GLT1 protein expression two (B) and six weeks...
Transplantation-based replacement of lost and/or dysfunctional astrocytes is a promising therapy for...
A major portion of spinal cord injury (SCI) cases affect midcervical levels, the location of the phr...
The GLT-1 and GLAST astroglial transporters are the glutamate transporters mainly involved in mainta...
<p><b>(A, B)</b>- Qualitative analysis of GAD65 and synaptophysin immuoreactivity showed normally ap...