<p>Single cell suspension from spleen, tumor draining lymph nodes, and tumor of control and MIP treated tumor bearing mice were analyzed for the expression of CD4 and FoxP3 by flow cytometry. In tumor microenvironment and tumor draining lymph node, the percentage of Treg cells were found to be lower in the MIP treated group as compared to control. In spleen comparable level of these cells were found in both, treated and untreated groups. () CD4+ cells; (––) CD4+FoxP3+ cells.</p
<p>(A) Foxp3 expression in freshly isolated CD4<sup>+</sup> T cells from the spleen, mesenteric lymp...
<p>Respectively on day 1, 3, 5, 7, 9 after treatment initiation in the independent treatment groups,...
<p>(<b>A</b>) Wild type (WT) or SCID BALB/c mice were inoculated at day 0 with 2×10<sup>5</sup> Renc...
<p>SL4-MUC1 cells (1×10<sup>6</sup> cells/50 µL) were injected into the space under the cecal serosa...
<p>C57BL/6 mice were challenged with E.G7 and then, 7 days post tumor challenge, were treated as ind...
<p>Cells were isolated from spleen and MLN on day 7, 14, 21, and 35 following DSS treatment and dete...
<p>SL4-MUC1 cells (1×10<sup>6</sup> cells/50 µL) were injected into the space under the cecal serosa...
To detect Tregs, spleens and MLNs were isolated to prepare single cell suspensions for CD4, CD25 and...
<p>At the termination of 3 months treatment, female NZB/W F<sub>1</sub> mice in vehicle and SM934 (1...
<p>(A) Mast cells regulate the infiltration of Treg cells. 5×10<sup>6</sup> BMMCs with or without an...
<p>WT and CCR4<sup>-/-</sup> mice were subjected to sham or CLP surgery and antibiotic treatment wit...
<p>(a), Splenocytes were stained with FITC-CD4 and PE-FoxP3 antibody, the frequencies of Treg cells ...
<p>A). At 12<sup>th</sup> day after tumor implantation and after one time VLP vaccination at day 3, ...
<p>Spleen of untreated- and 4NQO-treated wildtype and IL-23R KO mice were immunostained for CD4<sup>...
<p>(<b>a</b>) Dot plots show the number of peripheral blood Tregs in PBS (i–iv) or JBS (v-,viii) fed...
<p>(A) Foxp3 expression in freshly isolated CD4<sup>+</sup> T cells from the spleen, mesenteric lymp...
<p>Respectively on day 1, 3, 5, 7, 9 after treatment initiation in the independent treatment groups,...
<p>(<b>A</b>) Wild type (WT) or SCID BALB/c mice were inoculated at day 0 with 2×10<sup>5</sup> Renc...
<p>SL4-MUC1 cells (1×10<sup>6</sup> cells/50 µL) were injected into the space under the cecal serosa...
<p>C57BL/6 mice were challenged with E.G7 and then, 7 days post tumor challenge, were treated as ind...
<p>Cells were isolated from spleen and MLN on day 7, 14, 21, and 35 following DSS treatment and dete...
<p>SL4-MUC1 cells (1×10<sup>6</sup> cells/50 µL) were injected into the space under the cecal serosa...
To detect Tregs, spleens and MLNs were isolated to prepare single cell suspensions for CD4, CD25 and...
<p>At the termination of 3 months treatment, female NZB/W F<sub>1</sub> mice in vehicle and SM934 (1...
<p>(A) Mast cells regulate the infiltration of Treg cells. 5×10<sup>6</sup> BMMCs with or without an...
<p>WT and CCR4<sup>-/-</sup> mice were subjected to sham or CLP surgery and antibiotic treatment wit...
<p>(a), Splenocytes were stained with FITC-CD4 and PE-FoxP3 antibody, the frequencies of Treg cells ...
<p>A). At 12<sup>th</sup> day after tumor implantation and after one time VLP vaccination at day 3, ...
<p>Spleen of untreated- and 4NQO-treated wildtype and IL-23R KO mice were immunostained for CD4<sup>...
<p>(<b>a</b>) Dot plots show the number of peripheral blood Tregs in PBS (i–iv) or JBS (v-,viii) fed...
<p>(A) Foxp3 expression in freshly isolated CD4<sup>+</sup> T cells from the spleen, mesenteric lymp...
<p>Respectively on day 1, 3, 5, 7, 9 after treatment initiation in the independent treatment groups,...
<p>(<b>A</b>) Wild type (WT) or SCID BALB/c mice were inoculated at day 0 with 2×10<sup>5</sup> Renc...