Rat Rem2 shRNAs reduced mEPSCs frequency in hippocampal neurons.

<p><i>A,</i> Exemplar recording of mEPSCs from neurons transfected with rRem2-targeted shRNAs or the control plasmid. <i>B,</i> and <i>C,</i> Summarized mEPSCs frequency and amplitude 4 (N = 6) and 10 d (N = 12) after transfection, showing that the mEPSCs frequency was reduced significantly at 10 d after transfection of shRNAs compared with control transfection (p = 0.006). There was no change in amplitude (p = 0.55).