<p><b>A</b>. Representative currents from a cell demonstrating the response to 50% Neurobasal (NB) in the absence and presence of 50 µM D-APV. MEM application (50% dilution) produced minimal current. In this and subsequent figures, cells were voltage-clamped at −30 mV to relieve Mg<sup>2+</sup> block of the NMDA receptor channel. Scale bar applies to all traces. <b>B</b>. Summary of the steady-state current amplitudes from 5 cells. Asterisk designates p<0.05 compared with sham (unpaired, two-tailed t-tests with Bonferroni correction for multiple comparisons). <b>C</b>. Representative traces from a cell demonstrating similar current amplitude generated by acutely applied Neurobasal (NB) diluted to 50% in standard saline and 0.5 µM glutamate ...
Postsynaptic currents were studied by whole cell recordings in visually identified large neurons of ...
Cerebral edema affects millions of people worldwide and is associated with a plethora of diseases, d...
1. Glutamate receptor (GluR) channels were studied in basket cells in the dentate gyrus of rat hippo...
<p><b>A</b>. Representative currents from a hippocampal neuron showing the response to acute applica...
<p>(A) The increase of intracellular calcium was triggered by application of 100 µM of glutamate. Th...
Neurobasal defined culture medium has been optimized for survival of rat embryonic hippocampal neuro...
<p><b>A.</b> Oscillations were induced in whole-cell current clamp in a ventral horn neuron (100 µM ...
Present thinking about the way that the NMDA (N-methyl-D-aspartate) class of glutamate receptor oper...
Patch-clamp techniques were used to record pharmacologically-isolated N-methyl-D-aspartate-mediated ...
<p>A) Time courses of AMPA and NMDA receptor-mediated conductances. Green dashed line indicates the ...
<p><b>A</b>. In current clamp mode with gramicidin-perforated patch clamp, the membrane potential of...
<p><b>A</b>. Photomicrographs from a single experiment showing toxicity resulting from fresh Neuroba...
<p><b>A.</b> Typical inward currents in response to three 500 mM L-glutamate pulses in neural cells ...
In the mammalian central nervous system (CNS) fast excitatory neurotransmission is mediated by ionot...
<p>(A) After the application of NMDA (100 µM), a robust inward current was produced (first) which wa...
Postsynaptic currents were studied by whole cell recordings in visually identified large neurons of ...
Cerebral edema affects millions of people worldwide and is associated with a plethora of diseases, d...
1. Glutamate receptor (GluR) channels were studied in basket cells in the dentate gyrus of rat hippo...
<p><b>A</b>. Representative currents from a hippocampal neuron showing the response to acute applica...
<p>(A) The increase of intracellular calcium was triggered by application of 100 µM of glutamate. Th...
Neurobasal defined culture medium has been optimized for survival of rat embryonic hippocampal neuro...
<p><b>A.</b> Oscillations were induced in whole-cell current clamp in a ventral horn neuron (100 µM ...
Present thinking about the way that the NMDA (N-methyl-D-aspartate) class of glutamate receptor oper...
Patch-clamp techniques were used to record pharmacologically-isolated N-methyl-D-aspartate-mediated ...
<p>A) Time courses of AMPA and NMDA receptor-mediated conductances. Green dashed line indicates the ...
<p><b>A</b>. In current clamp mode with gramicidin-perforated patch clamp, the membrane potential of...
<p><b>A</b>. Photomicrographs from a single experiment showing toxicity resulting from fresh Neuroba...
<p><b>A.</b> Typical inward currents in response to three 500 mM L-glutamate pulses in neural cells ...
In the mammalian central nervous system (CNS) fast excitatory neurotransmission is mediated by ionot...
<p>(A) After the application of NMDA (100 µM), a robust inward current was produced (first) which wa...
Postsynaptic currents were studied by whole cell recordings in visually identified large neurons of ...
Cerebral edema affects millions of people worldwide and is associated with a plethora of diseases, d...
1. Glutamate receptor (GluR) channels were studied in basket cells in the dentate gyrus of rat hippo...