a<p>For exposures to ferrets 2-C and 2-D, the diffusion dryer was inserted into the line exiting the Collison generator, reducing the humidity at the end of the hour nebulization.</p>b<p>Calculation of inhaled virus based on measured viral RNA in aerosol inhaled during 60 min of aerosol exposure.</p>c<p>Nasal wash was collected on day 2 post exposure (pe) in Exp 1, and daily in Exp 2; culture results are reported for the entire collection as FFU/mL; viral RNA is the peak titer on day 3 pe and is reported as GEq/collection.</p
<p>Four ferrets were inoculated with 10<sup>4</sup> PFU of E195-I219K. For 30 hours between days 1 a...
<p>(<b>A</b>) <b>Viral replication of influenza A/California/07/2009 in nasal washes following intra...
<p>Transmission of Cal/04 between donors infected by nebulized virus and recipients exposed continuo...
<p>a. Actual dose calculated was within 30% of target dose.</p><p>b. Calculations based on viral RNA...
<p>Three ferrets each were housed under the designated environmental conditions and were presented w...
<p>Aerosol volumes were measured from ferrets during 15 minutes of normal breathing (NB) or 5 minute...
Nasal washes were collected at +1 to +8 dpi, 11 dpi and 14 dpi for Groups 2–5. Group 1 had nasal was...
Influenza virus is a major cause of morbidity and mortality worldwide, yet little quantitative under...
<p>Three ferrets each were housed under the designated environmental conditions and were presented w...
<p>Virus titers in throat (black bars) and nose swabs (grey bars) are displayed for inoculated (Pane...
<p>Virus titers in throat (black bars) and nose swabs (grey bars) are displayed for inoculated (Pane...
<p>Ferrets were infected intra-nasally, and nasal washes were collected at the intervals shown for v...
<p>Three ferrets each were housed under the designated environmental conditions and were presented w...
<p>Immunocompetent (blue) and immunocompromised (red, green) ferrets were inoculated with influenza ...
<p>Two pairs (designated A and B) of donor ferrets (designated donor1 and donor2 of pair A, donor3 a...
<p>Four ferrets were inoculated with 10<sup>4</sup> PFU of E195-I219K. For 30 hours between days 1 a...
<p>(<b>A</b>) <b>Viral replication of influenza A/California/07/2009 in nasal washes following intra...
<p>Transmission of Cal/04 between donors infected by nebulized virus and recipients exposed continuo...
<p>a. Actual dose calculated was within 30% of target dose.</p><p>b. Calculations based on viral RNA...
<p>Three ferrets each were housed under the designated environmental conditions and were presented w...
<p>Aerosol volumes were measured from ferrets during 15 minutes of normal breathing (NB) or 5 minute...
Nasal washes were collected at +1 to +8 dpi, 11 dpi and 14 dpi for Groups 2–5. Group 1 had nasal was...
Influenza virus is a major cause of morbidity and mortality worldwide, yet little quantitative under...
<p>Three ferrets each were housed under the designated environmental conditions and were presented w...
<p>Virus titers in throat (black bars) and nose swabs (grey bars) are displayed for inoculated (Pane...
<p>Virus titers in throat (black bars) and nose swabs (grey bars) are displayed for inoculated (Pane...
<p>Ferrets were infected intra-nasally, and nasal washes were collected at the intervals shown for v...
<p>Three ferrets each were housed under the designated environmental conditions and were presented w...
<p>Immunocompetent (blue) and immunocompromised (red, green) ferrets were inoculated with influenza ...
<p>Two pairs (designated A and B) of donor ferrets (designated donor1 and donor2 of pair A, donor3 a...
<p>Four ferrets were inoculated with 10<sup>4</sup> PFU of E195-I219K. For 30 hours between days 1 a...
<p>(<b>A</b>) <b>Viral replication of influenza A/California/07/2009 in nasal washes following intra...
<p>Transmission of Cal/04 between donors infected by nebulized virus and recipients exposed continuo...