Analysis of lipids and xenobiotics target genes expression in the liver.

<p>Relative gene expressions of <i>scd-1</i>, <i>fasn</i>, <i>cd36</i>, <i>acox</i>, <i>cyp2B10</i> and <i>cyp3A11</i> were quantified in liver samples from 12-week old (Fig. 5A) and 25-week old (Fig. 5B) mice by real-time time PCR. Similarly, <i>scd-1, cyp7a1</i> and <i>pltp</i> expressions were quantified in 35-week old mice (Fig. 5C); wild-type (open bars) and mdr1ab-/- (solid bars). Values were normalized to TBP gene and expressed as arbitrary unit. Values shown are means ± s.e.m (n = 3). Differences are considered significant when <i>p</i><0.05. *, <i>p</i><0.05; **, <i>p</i><0.01; ***, <i>p</i><0.001.