BrdU-labelled cells predominantly adopt a neuronal fate.

<p>Images show representative images from a MS-exposed female kindled rat brain (left panels) and an EH-exposed kindled female rat brain (right panels). Panels (i) and (ii) display NeuN+ve cells in green, indicative of mature neurons. Panels (iii) and (iv) display BrdU+ve cells in red, indicative of newly synthesised cells. Panels (v) and (vi) represent GFAP+ve glial cells in blue. Panels (vii) and (viii) represent the merged images of the three panels above, and panels (ix) and (x) are enlarged sections of the boxed areas in panels (vii) and (viii), respectively. Note the pink arrows indicating cells yellow cells in panels (vii) – (x), the product of double-labelling with NeuN (green) and BrdU (red), and indicative of newly generated neurons.