<p>The minimal inhibitory concentration of RpSP-D and NpSP-D required to inhibit the hemagglutination by all 27 H1N1 and H3N2 IAVs was assessed (A). The horizontal line indicates the average of the minimal inhibitory concentration for both preparations which did not differ significantly. The values were also compared directly (B). The minimal inhibition concentrations of RpSP-D correlated well with those of NpSP-D. Each symbol in panels A and B represent an individual IAV strain.</p
Influenza is a major burden to public health. Due to high mutation rates and selection pressure, mut...
1<p>Neutralisation of laboratory adapted X-181 strain corresponding to A/California/07/2009 (H1N1)pd...
<p>Aliquots of the Phil82 H3N2 (panel A) or Cal09 H1N1 (panel B) viral strains were incubated with t...
<p>Using the infection reduction assay, the neutralization of IAV by various doses of RpSP-D was ass...
<p>(A) Chemical structures of the obligate chain terminator 3′dGTP and the base-modified T-705 ribof...
a<p>The reciprocal of the highest dilution of serum that prevented hemagglutination is shown for thr...
The target protein (enzyme) with which antiviral agents interact determines their antiviral activity...
a<p>For the hemagglutination inhibition test, the titers of the virus and pp were adjusted to 4 hema...
The armamentarium of antiviral drugs against influenza viruses is limited. Furthermore, influenza vi...
a<p>The required concentration to reduce 50% of plaque formation (EC<sub>50</sub>) was calculated by...
(A–H) HI activity of F045-092 IgG1, monomeric (Mo) IgA1, dimeric (Di) SIgA1, tetrameric (Te) SIgA1, ...
Estimated inhibition percentage (A), percentage reduction in the basic reproduction number R0 (B) an...
<p>Guinea pig sera were incubated with (A) H1N1 viruses, (B) H1N1pdm viruses, or (C) H3N2 viruses. T...
Colored lines depict the concentration-prophylaxis profile for an average drug class-specific slope ...
The influenza virus neuraminidase inhibitor RWJ-270201 (cyclopentane carboxylic acid, 3-[cis-1-(acet...
Influenza is a major burden to public health. Due to high mutation rates and selection pressure, mut...
1<p>Neutralisation of laboratory adapted X-181 strain corresponding to A/California/07/2009 (H1N1)pd...
<p>Aliquots of the Phil82 H3N2 (panel A) or Cal09 H1N1 (panel B) viral strains were incubated with t...
<p>Using the infection reduction assay, the neutralization of IAV by various doses of RpSP-D was ass...
<p>(A) Chemical structures of the obligate chain terminator 3′dGTP and the base-modified T-705 ribof...
a<p>The reciprocal of the highest dilution of serum that prevented hemagglutination is shown for thr...
The target protein (enzyme) with which antiviral agents interact determines their antiviral activity...
a<p>For the hemagglutination inhibition test, the titers of the virus and pp were adjusted to 4 hema...
The armamentarium of antiviral drugs against influenza viruses is limited. Furthermore, influenza vi...
a<p>The required concentration to reduce 50% of plaque formation (EC<sub>50</sub>) was calculated by...
(A–H) HI activity of F045-092 IgG1, monomeric (Mo) IgA1, dimeric (Di) SIgA1, tetrameric (Te) SIgA1, ...
Estimated inhibition percentage (A), percentage reduction in the basic reproduction number R0 (B) an...
<p>Guinea pig sera were incubated with (A) H1N1 viruses, (B) H1N1pdm viruses, or (C) H3N2 viruses. T...
Colored lines depict the concentration-prophylaxis profile for an average drug class-specific slope ...
The influenza virus neuraminidase inhibitor RWJ-270201 (cyclopentane carboxylic acid, 3-[cis-1-(acet...
Influenza is a major burden to public health. Due to high mutation rates and selection pressure, mut...
1<p>Neutralisation of laboratory adapted X-181 strain corresponding to A/California/07/2009 (H1N1)pd...
<p>Aliquots of the Phil82 H3N2 (panel A) or Cal09 H1N1 (panel B) viral strains were incubated with t...