TNFα-induced NFκB activity at 18 hours is significantly reduced by CSE.

<p>Cells transfected with reporter constructs for NFκB (grey bars) or those with the NFκB binding sites removed (ΔκB, white bars) were stimulated for 18 hours with combinations of CSE (<b><i>C</i></b>), nicotine (<b><i>N</i></b>) and TNFα (<b><i>T</i></b>). Results (of 5 experiments) were normalised against a transfection control and NFκB activity is expressed relative to that in unstimulated cells, which were given a value of 1. A Friedman test showed a significant different in those cells stimulated with <b><i>T</i></b>, <b><i>TC</i></b>, <b><i>TN</i></b> and <b><i>TCN</i></b>.