<p>6 out of 19 (31.6%) and 2 out of 15 (13.3%) HLA-A2<sup>+</sup> recovered individuals responded above cutoff value (horizontal bar in each plot defined as mean + 2SD CD8<sup>+</sup>/IFN-γ<sup>+</sup> response in HLA-A2<sup>−</sup> controls) against peptide pools II and IV, respectively. Fischer's exact probability test showed that the response in peptide pool II is statistically significant.</p
<p>Mice were depleted of CD4<sup>+</sup> and/or CD8<sup>+</sup> cells 5 and 2 days before immunisati...
Peptide pools are routinely used to study antigen specific T cell responses, both in epitope discove...
<p>PBMCs were isolated from freshly or prospectively collected blood samples at M12 post-transplanta...
<p>IFN-γ production was measured in culture supernatants of HLA-A2<sup>+</sup> recovered individuals...
<p>(A) SFC per million PBMCs of patients with (red) and without (blue) warning signs in response to ...
<p><i>(</i><b><i>A</i></b><i>),</i> the correlation of IFN-γ IDOlong responses with the class I tiss...
<p>ELISpot analysis (upper row) of a negative responder (HLA-A2<sup>−</sup> recovered individual) (A...
<p>PBMC from healthy donors, breast cancer patients, melanoma patients, and renal cell carcinoma pat...
<p>A. Splenocytes from a total of 5 mice immunized with polytope construct three times with one week...
<p>Freezed/thawed antigens of <i>L. major</i> were used to stimulate the PBMCs in culture as previou...
<p>The y-axis shows the magnitude of CD4+ and CD8+T-cells on a half-log scale across groups A-D for ...
<p>(A) In blue wildtype peptide recognition, in red mutated peptide recognition at first and second ...
<p>IFN-γ-positive spots were detected in the PHA (the positive control), P2 and P4 groups, whereas o...
<p>(<b>A</b>) Frequency of HCV-tetramer<sup>+</sup> CD8<sup>+</sup> T cells after 10 days <i>in vitr...
<p>Representative examples of longitudinal responses are shown for HLA-B*35 -Px+ Subjects 1 (A) and ...
<p>Mice were depleted of CD4<sup>+</sup> and/or CD8<sup>+</sup> cells 5 and 2 days before immunisati...
Peptide pools are routinely used to study antigen specific T cell responses, both in epitope discove...
<p>PBMCs were isolated from freshly or prospectively collected blood samples at M12 post-transplanta...
<p>IFN-γ production was measured in culture supernatants of HLA-A2<sup>+</sup> recovered individuals...
<p>(A) SFC per million PBMCs of patients with (red) and without (blue) warning signs in response to ...
<p><i>(</i><b><i>A</i></b><i>),</i> the correlation of IFN-γ IDOlong responses with the class I tiss...
<p>ELISpot analysis (upper row) of a negative responder (HLA-A2<sup>−</sup> recovered individual) (A...
<p>PBMC from healthy donors, breast cancer patients, melanoma patients, and renal cell carcinoma pat...
<p>A. Splenocytes from a total of 5 mice immunized with polytope construct three times with one week...
<p>Freezed/thawed antigens of <i>L. major</i> were used to stimulate the PBMCs in culture as previou...
<p>The y-axis shows the magnitude of CD4+ and CD8+T-cells on a half-log scale across groups A-D for ...
<p>(A) In blue wildtype peptide recognition, in red mutated peptide recognition at first and second ...
<p>IFN-γ-positive spots were detected in the PHA (the positive control), P2 and P4 groups, whereas o...
<p>(<b>A</b>) Frequency of HCV-tetramer<sup>+</sup> CD8<sup>+</sup> T cells after 10 days <i>in vitr...
<p>Representative examples of longitudinal responses are shown for HLA-B*35 -Px+ Subjects 1 (A) and ...
<p>Mice were depleted of CD4<sup>+</sup> and/or CD8<sup>+</sup> cells 5 and 2 days before immunisati...
Peptide pools are routinely used to study antigen specific T cell responses, both in epitope discove...
<p>PBMCs were isolated from freshly or prospectively collected blood samples at M12 post-transplanta...