Differentiating MEL cells display similar characteristics irrespective to the level of PrP^C expression.

<p>(<b>A</b>) Growth curves of LP1, LP2 and control LN lines during erythroid differentiation induced by HMBA. (<b>B</b>) Cell viability based on a Trypan Blue exclusion assay. (<b>C</b>) Concentration of total hemoglobin in the cells per 100 µg/mL of total cell proteins. (<b>D</b>) Number of CD71 (transferrin receptor) molecules per cell, analyzed by quantitative flow cytometry, based on assumption that one anti- CD71-PE mAb binds one molecule of transferrin receptor.