RAMB treatment fails to inhibit proteasomal activity in living cells.

<p><i>Left panel:</i> Luciferase activity in lysates of Ub-FL or FL-vector transfected cells either with or without treatment with RAMB compounds or Bortezomib were quantified in Relative Luminescence Units (RLU) and expressed as % of control. Error bars are Standard Deviation (SD) for three independent experiments. <i>Middle panel:</i> Quantification of the Ub-FL/FL ratio. <i>Right panel:</i> Luminescence activity in cell lysates derived from CaSki cervical cancer cells with or without RAMB or Botezomib treatment quantified in Relative Luminescence Units (RLUs). *, P<0.05, **, P<0.02.