Test for activity <i>in vivo</i> of compounds active <i>in vitro</i>.

<p>Groups of five mice were infected with <i>T. cruzi</i> and treated with different compounds following the protocol shown in (A). (B) Quantification of parasite infection levels in the groups of mice treated with the different compounds is expressed as <i>T. cruzi</i> index. Compounds are identified by their CID. Results are expressed as average ± standard deviation (*, <i>P</i><0.05). (C) One representative mouse of each group treated with compounds CID-12402750 and CID-24892493.