<p>PBMC from MVA85A-vaccinated subjects were plated out at 5×10<sup>4</sup> cells/well in 50 µL. Cells were incubated with either 50 µM ATP or 50 µM+100 µM ARL67156 before addition of the luciferase reagent. A standard curve starting at 50 µM ATP was set up and negative controls were cells with no ATP added. (A) Shows change in ATP consumption over time post-vaccination. (B) Paired representation of change in ATP consumption between 0 and 2 weeks post-MVA85A. Effect of addition of ARL67156 is show in (C). (n = 10–12). Note that the observation of a greater effect of the inhibitor is potentially due to saturation of binding sites for ATP by the inhibitor at this timepoint, whereas the greater percentage of CD39<sup>+</sup> cells present at o...
<p>(<b>A</b>) The average time course of relative changes in ΔF<sub>340</sub>/F<sub>380</sub> in res...
<p>(Left) The indicated cell lines were pretreated with 10 µM PSI-6130 for 3 days or were cultured i...
<p>(<b>A</b>) YVAD (5 mg/kg), Apyrase (50 U/kg) or BBG (60 mg/kg) pre-injection prior to ATP reduced...
Ntrations of ATP. Next, cells were extensively washed and co-cultured for 3 days with heterologous C...
<p>A–F) Neutrophils (▪,□) and PBMC (•,○) were incubated with (▪, •) or without (□, ○) 5 mM glucose. ...
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against di...
<p><b>Copyright information:</b></p><p>Taken from "Molecular mechanisms of extracellular adenine nuc...
On of 293T cells (A) or following acute infection of CD4T cells (B). In some experiments, iDCs were ...
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against di...
<p>(A) Washed human platelets were preincubated with a mixture of phosphodiesterase inhibitors for 5...
<p><b>Copyright information:</b></p><p>Taken from "Molecular mechanisms of extracellular adenine nuc...
<p>Spleen cells from 3 to 4-mo-old MRL<i><sup>+/+</sup></i> (<i>solid line</i>), MRL/<i>lpr</i> (<i>...
Extracellular ATP has been shown to increase the permeability of cells via the P2X7 receptor. This r...
It has been reported that ATP inhibits or stimulates lymphoid cell proliferation depending on the ce...
It has been reported that ATP inhibits or stimulates lymphoid cell proliferation depending on the ce...
<p>(<b>A</b>) The average time course of relative changes in ΔF<sub>340</sub>/F<sub>380</sub> in res...
<p>(Left) The indicated cell lines were pretreated with 10 µM PSI-6130 for 3 days or were cultured i...
<p>(<b>A</b>) YVAD (5 mg/kg), Apyrase (50 U/kg) or BBG (60 mg/kg) pre-injection prior to ATP reduced...
Ntrations of ATP. Next, cells were extensively washed and co-cultured for 3 days with heterologous C...
<p>A–F) Neutrophils (▪,□) and PBMC (•,○) were incubated with (▪, •) or without (□, ○) 5 mM glucose. ...
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against di...
<p><b>Copyright information:</b></p><p>Taken from "Molecular mechanisms of extracellular adenine nuc...
On of 293T cells (A) or following acute infection of CD4T cells (B). In some experiments, iDCs were ...
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against di...
<p>(A) Washed human platelets were preincubated with a mixture of phosphodiesterase inhibitors for 5...
<p><b>Copyright information:</b></p><p>Taken from "Molecular mechanisms of extracellular adenine nuc...
<p>Spleen cells from 3 to 4-mo-old MRL<i><sup>+/+</sup></i> (<i>solid line</i>), MRL/<i>lpr</i> (<i>...
Extracellular ATP has been shown to increase the permeability of cells via the P2X7 receptor. This r...
It has been reported that ATP inhibits or stimulates lymphoid cell proliferation depending on the ce...
It has been reported that ATP inhibits or stimulates lymphoid cell proliferation depending on the ce...
<p>(<b>A</b>) The average time course of relative changes in ΔF<sub>340</sub>/F<sub>380</sub> in res...
<p>(Left) The indicated cell lines were pretreated with 10 µM PSI-6130 for 3 days or were cultured i...
<p>(<b>A</b>) YVAD (5 mg/kg), Apyrase (50 U/kg) or BBG (60 mg/kg) pre-injection prior to ATP reduced...